Isotopically Labeled Compounds
Medchemexpress LLC Nintedanib-d8 | 1624587-87-6 | 99.9% | C31H25D8N5O4 | 5 MG
Nintedanib-d8 is a deuterium labeled Nintedanib, which is a potent triple angiokinase inhibitor targeting VEGFR1/2/3, FGFR1/2/3, and PDGFRα/β.
- Used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC 3,5-Pyridinedicarboxylic acid, 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethyl-, 3-ethyl 5-methyl ester-d3 | 1219795-30-8 | 99.8% | 1 MG
Felodipine-d3 is a deuterium-labeled variant of Felodipine, a potent dihydropyridine calcium channel antagonist. It lowers blood pressure by selectively acting on vascular smooth muscle. This anti-hypertensive agent induces autophagy and can cross the blood-brain barrier. It is suitable for research use only and can be used as a tracer or an internal standard for quantitative analysis.
- Potent vasoselective calcium channel antagonist
- Lowers blood pressure by selective action on vascular smooth muscle
- Induces autophagy
- Can cross the blood-brain barrier
- Suitable for research use only
- Used as a tracer
- Used as an internal standard for quantitative analysis via NMR, GC-MS, or LC-MS
Sigma Aldrich Fine Chemicals Biosciences Pyridine 15N 98 atom 15N500MG
Pyridine 15N 98 atom 15N500MG
Medchemexpress LLC Metoprolol-d7 hydrochloride | 1219798-61-4 | 99.7% | 310.87 | 5 MG
Metoprolol-d7 hydrochloride is a deuterium-labeled form of Metoprolol, an orally active, selective β1-adrenoceptor antagonist. It demonstrates anti-inflammatory, antitumor, and anti-angiogenic properties.
- Deuterium labeled compound
- Selective β1-adrenoceptor antagonist
- Exhibits anti-inflammatory, antitumor, and anti-angiogenic properties
- Can be used as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC Bumetanide-d5 | 1216739-35-3 | 99.8% | 369.45 | 5 MG
Bumetanide-d5 is a deuterium-labeled Bumetanide. It functions as a selective Na+-K+-Cl- (NKCC1) inhibitor and weakly inhibits NKCC2, with IC50s of 0.68 and 4.0 μM for hNKCC1A and hNKCC2A, respectively. This compound is suitable for use as a tracer and as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Deuterium labeled Bumetanide
- Selective Na+-K+-Cl- (NKCC1) inhibitor
- Weakly inhibits NKCC2
- Functions as a tracer
- Functions as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
- Appearance: Solid
- Color: White to off-white
Cambridge Isotope Laboratories AMINOPYRINE (N,N-DIMETHYL-13C2, 99%), 1 G, 60433-90-1
AMINOPYRINE (N,N-DIMETHYL-13C2, 99%), 1 G, 60433-90-1
Cambridge Isotope Laboratories GLYCINE (1-13C, 99%), 5 G, 20110-59-2
GLYCINE (1-13C, 99%), 5 G, 20110-59-2
Medchemexpress LLC Pyrene-d10 | 1718-52-1 | C16D10 | 100 MG
Pyrene-d10 is the deuterium labeled Pyrene. Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Can be used as a tracer.
- Can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Sarcosine-d3 25mg
Sarcosine-d3 is the deuterium labeled Sarcosine Sarcosine (N-Methylglycine) an endogenous amino acid is a competitive glycine transporter type I (GlyT1) inhibitor and N-methyl-D-aspartate (NMDA) receptor co-agonist Sarcosine increases the glycine concentration resulting in an indirect potentiation of the NMDA receptor Sarcosine is commonly used for the research of schizophrenia1]2]
Cambridge Isotope Laboratories 4-MonoBDE (BDE-3) (13C12 99%) 50 ug/mL in nonane 1 2 mL
4-MonoBDE (BDE-3) (13C12 99%) 50 ug/mL in nonane 1 2 mL
Cambridge Isotope Laboratories Benzaldehyde (carbonyl-13C 99%) 0 1% hydroquinone 1 g
Benzaldehyde (carbonyl-13C 99%) 0 1% hydroquinone 1 g
Medchemexpress LLC Sorafenib-d3 (Donafenib) | 1130115-44-4 | MFCD08460931 | 99.6% | 467.84 g/mol | C21H13D3ClF3N4O3 | 1 ML
Sorafenib-d3 is the deuterium-labeled analogue of the multikinase inhibitor sorafenib, supplied as a ready-to-use 10 mM solution in DMSO for research applications, including use as an analytical standard and in pharmacological studies.
- Deuterium-labeled compound for use as an internal standard.
- Ready-to-use 10 mM solution in DMSO, 1 mL.
- High purity (99.6%) suitable for analytical use.
- Suitable for biochemical and pharmacological research.
- Molecular formula C21H13D3ClF3N4O3; molecular weight 467.84 g/mol.
Medchemexpress LLC Monoolein-d5 | 565183-24-6 | MFCD27992100 | 99.9% | 361.57 g/mol | C21H35D5O4 | 5 MG
Monoolein-d5 is the deuterium-labeled analogue of monoolein provided as a research-grade reference standard for analytical and tracer studies. It is suitable for use in mass spectrometry, metabolite identification, and isotopic labeling experiments. For research use only.
Medchemexpress LLC Glyphosate-d2-1 | 1071-83-6 | MFCD00055350 | 99.9% | 171.09 | C3H6D2NO5P | 10 MG
Glyphosate-d2-1 is a deuterium-labeled analytical standard of glyphosate supplied in milligram quantities for use in analytical and research applications. It is intended as an isotopically labeled internal standard to improve quantitation and identification in mass spectrometry and other analytical methods.
- Deuterium-labeled glyphosate for use as an internal standard.
- Supplied in milligram-scale quantity suitable for analytical workflows.
- High listed purity for trace-level quantitation.
- Accompanied by datasheet, certificate of analysis, and spectral reports.
- Suitable for LC-MS/MS method development and validation.
Cayman Chemical DeoxycholIc AcId 10g
A secondary bile acid; inhibits TCA-induced spore germination in seven C. difficile strains at 0.2% v/v; inhibits growth and decreases the cytotoxicity of C. difficile culture supernatants to Vero cells at 0.02% v/v; inhibits ionizing radiation-induced p53-dependent transcription in a reporter assay using HCT116 cells at 200 µM; fecal and intestinal tissue levels are increased in a rat model of high-fat diet-induced obesity compared with rats fed a normal diet; increased serum levels have been found in patients with colorectal cancer